F79Y (p.Phe79Tyr) variant of LEPR (Leptin receptor)
F79Y (p.Phe79Tyr) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
F79Y (p.Phe79Tyr) variant details
- p.Phe79Tyr
- gnomAD 1-65570668-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.06
- CADD 8.55
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available