C3C (p.Cys3Cys) variant of LEPR (Leptin receptor)
C3C (p.Cys3Cys) in LEPR (Leptin receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
C3C (p.Cys3Cys) variant details
- p.Cys3Cys
- gnomAD 1-65565574-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.454
- CADD 13.10
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available