C37W (p.Cys37Trp) variant of LEPR (Leptin receptor)
C37W (p.Cys37Trp) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
C37W (p.Cys37Trp) variant details
- p.Cys37Trp
- gnomAD 1-65570543-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- REVEL 0.70
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available