A67D (p.Ala67Asp) variant of LEPR (Leptin receptor)
A67D (p.Ala67Asp) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A67D (p.Ala67Asp) variant details
- p.Ala67Asp
- ExAC rs573025358
- TOPMed rs573025358
- gnomAD rs573025358
- Missense
- Variant Prioritization Score for Impact Estimate 0.078
- REVEL 0.07
- CADD 4.24
- PolyPhen-2 0.13
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available