A51P (p.Ala51Pro) variant of LEPR (Leptin receptor)
A51P (p.Ala51Pro) in LEPR (Leptin receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
A51P (p.Ala51Pro) variant details
- p.Ala51Pro
- 1000Genomes rs201975519
- ExAC rs201975519
- gnomAD rs201975519
- Missense
- Variant Prioritization Score for Impact Estimate 0.0486
- REVEL 0.04
- CADD 1.88
- PolyPhen-2 0.02
- SIFT 0.15
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available