A21A (p.Ala21Ala) variant of LEPR (Leptin receptor)
A21A (p.Ala21Ala) in LEPR (Leptin receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
A21A (p.Ala21Ala) variant details
- p.Ala21Ala
- rs148155161
- gnomAD 1-65570495-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.101
- CADD 2.90
- Most common in the African/African-American population (allele frequency 0.00019)
- Structural context available
- Literature evidence available