T21P (p.Thr21Pro) variant of LDLR (Low-density lipoprotein receptor)
T21P (p.Thr21Pro) in LDLR (Low-density lipoprotein receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T21P (p.Thr21Pro) variant details
- p.Thr21Pro
- Ensembl rs2147186706
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- CADD 9.45
- PolyPhen-2 0.02
- SIFT 0.11
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available