Q35R (p.Gln35Arg) variant of LDLR (Low-density lipoprotein receptor)
Q35R (p.Gln35Arg) in LDLR (Low-density lipoprotein receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
Q35R (p.Gln35Arg) variant details
- p.Gln35Arg
- TOPMed rs2077193348
- Missense
- Variant Prioritization Score for Impact Estimate 0.0726
- CADD 0.03
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available