Q35P (p.Gln35Pro) variant of LDLR (Low-density lipoprotein receptor)
Q35P (p.Gln35Pro) in LDLR (Low-density lipoprotein receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
Q35P (p.Gln35Pro) variant details
- p.Gln35Pro
- gnomAD 19-11100259-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- MetaLR 0.54
- MetaSVM -0.33
- CADD 0.43
- PolyPhen-2 0.17
- SIFT 0.28
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available
- Literature evidence available