L14L (p.Leu14Leu) variant of LDLR (Low-density lipoprotein receptor)
L14L (p.Leu14Leu) in LDLR (Low-density lipoprotein receptor) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
L14L (p.Leu14Leu) variant details
- p.Leu14Leu
- gnomAD 19-11089590-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.45
- CADD 8.37
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available