G24S (p.Gly24Ser) variant of LDLR (Low-density lipoprotein receptor)
G24S (p.Gly24Ser) in LDLR (Low-density lipoprotein receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G24S (p.Gly24Ser) variant details
- p.Gly24Ser
- gnomAD rs1767610199
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- CADD 12.30
- PolyPhen-2 0.06
- SIFT 0.46
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available