E10del (p.Glu10del) variant of LCK (Tyrosine-protein kinase Lck)
E10del (p.Glu10del) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E10del (p.Glu10del) variant details
- rs1244165498
- gnomAD 1-32274356-GGAA-G
- Inframe Deletion
- Variant Prioritization Score for Impact Estimate 0.39
- CADD 19.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.019
- Literature evidence available