p.Asp29 Ala33del variant of LCK (Tyrosine-protein kinase Lck)
p.Asp29 Ala33del in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
p.Asp29 Ala33del variant details
- gnomAD 1-32274270-GTTGGG
- Inframe Deletion
- Variant Prioritization Score for Impact Estimate 0.7
- CADD 10.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.234
- Literature evidence available