Y51Y (p.Tyr51Tyr) variant of LCK (Tyrosine-protein kinase Lck)
Y51Y (p.Tyr51Tyr) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y51Y (p.Tyr51Tyr) variant details
- p.Tyr51Tyr
- rs950834998
- gnomAD 1-32274784-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0902
- CADD 1.35
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.0373
- Literature evidence available