W13C (p.Trp13Cys) variant of LCK (Tyrosine-protein kinase Lck)
W13C (p.Trp13Cys) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
W13C (p.Trp13Cys) variant details
- p.Trp13Cys
- rs1640186761
- gnomAD 1-32274236-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- CADD 13.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.18
- Literature evidence available