V28V (p.Val28Val) variant of LCK (Tyrosine-protein kinase Lck)
V28V (p.Val28Val) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V28V (p.Val28Val) variant details
- p.Val28Val
- rs144437329
- gnomAD 1-32274413-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.145
- CADD 9.10
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.459
- Literature evidence available