T50T (p.Thr50Thr) variant of LCK (Tyrosine-protein kinase Lck)
T50T (p.Thr50Thr) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
T50T (p.Thr50Thr) variant details
- p.Thr50Thr
- gnomAD 1-32274329-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.72
- CADD 20.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- LCK SH3 domain domainome 1.0: score -1.08
- Literature evidence available