S7T (p.Ser7Thr) variant of LCK (Tyrosine-protein kinase Lck)
S7T (p.Ser7Thr) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S7T (p.Ser7Thr) variant details
- p.Ser7Thr
- gnomAD 1-32274264-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.643
- CADD 10.80
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.54
- Literature evidence available