S7C (p.Ser7Cys) variant of LCK (Tyrosine-protein kinase Lck)
S7C (p.Ser7Cys) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S7C (p.Ser7Cys) variant details
- p.Ser7Cys
- rs1640187491
- gnomAD 1-32274265-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- CADD 13.70
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.54
- Literature evidence available