S6F (p.Ser6Phe) variant of LCK (Tyrosine-protein kinase Lck)
S6F (p.Ser6Phe) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S6F (p.Ser6Phe) variant details
- p.Ser6Phe
- gnomAD 1-32274214-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- CADD 4.09
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.99
- Literature evidence available