R45R (p.Arg45Arg) variant of LCK (Tyrosine-protein kinase Lck)
R45R (p.Arg45Arg) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
R45R (p.Arg45Arg) variant details
- p.Arg45Arg
- gnomAD 1-32274829-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.19
- CADD 4.74
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.357
- Literature evidence available