Q62E (p.Gln62Glu) variant of LCK (Tyrosine-protein kinase Lck)
Q62E (p.Gln62Glu) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Q62E (p.Gln62Glu) variant details
- p.Gln62Glu
- ExAC rs764357331
- gnomAD rs764357331
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.06
- CADD 16.80
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available