P60S (p.Pro60Ser) variant of LCK (Tyrosine-protein kinase Lck)
P60S (p.Pro60Ser) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
P60S (p.Pro60Ser) variant details
- p.Pro60Ser
- gnomAD 1-32274809-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.10
- CADD 21.60
- PolyPhen-2 0.21
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available