P60L (p.Pro60Leu) variant of LCK (Tyrosine-protein kinase Lck)
P60L (p.Pro60Leu) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P60L (p.Pro60Leu) variant details
- p.Pro60Leu
- ExAC rs752903747
- gnomAD rs752903747
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.12
- CADD 23.70
- PolyPhen-2 0.37
- SIFT 0.01
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available