P57P (p.Pro57Pro) variant of LCK (Tyrosine-protein kinase Lck)
P57P (p.Pro57Pro) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P57P (p.Pro57Pro) variant details
- p.Pro57Pro
- rs528967735
- gnomAD 1-32274802-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0963
- CADD 2.21
- Most common in the 1KG:STU population (allele frequency 0.01)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.176
- Literature evidence available