P47P (p.Pro47Pro) variant of LCK (Tyrosine-protein kinase Lck)
P47P (p.Pro47Pro) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P47P (p.Pro47Pro) variant details
- p.Pro47Pro
- rs745339412
- gnomAD 1-32274772-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.161
- CADD 11.40
- Most common in the Latino/Admixed American population (allele frequency 0.00098)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.836
- Literature evidence available