N16K (p.Asn16Lys) variant of LCK (Tyrosine-protein kinase Lck)
N16K (p.Asn16Lys) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
N16K (p.Asn16Lys) variant details
- p.Asn16Lys
- rs1475748793
- gnomAD 1-32274239-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- CADD 4.60
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.218
- Literature evidence available