L61R (p.Leu61Arg) variant of LCK (Tyrosine-protein kinase Lck)
L61R (p.Leu61Arg) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L61R (p.Leu61Arg) variant details
- p.Leu61Arg
- TOPMed rs1476466097
- gnomAD rs1476466097
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.10
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available