L48L (p.Leu48Leu) variant of LCK (Tyrosine-protein kinase Lck)
L48L (p.Leu48Leu) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L48L (p.Leu48Leu) variant details
- p.Leu48Leu
- rs771590192
- gnomAD 1-32274773-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.497
- CADD 12.30
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score 0.0011
- Literature evidence available