L30L (p.Leu30Leu) variant of LCK (Tyrosine-protein kinase Lck)
L30L (p.Leu30Leu) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L30L (p.Leu30Leu) variant details
- p.Leu30Leu
- rs1303366697
- gnomAD 1-32274417-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.373
- CADD 12.60
- Most common in the East Asian population (allele frequency 0.00038)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.362
- Literature evidence available