L30F (p.Leu30Phe) variant of LCK (Tyrosine-protein kinase Lck)
L30F (p.Leu30Phe) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L30F (p.Leu30Phe) variant details
- p.Leu30Phe
- gnomAD 1-32274285-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- CADD 5.88
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.362
- Literature evidence available