G41G (p.Gly41Gly) variant of LCK (Tyrosine-protein kinase Lck)
G41G (p.Gly41Gly) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G41G (p.Gly41Gly) variant details
- p.Gly41Gly
- gnomAD 1-32274754-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.486
- CADD 12.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.65
- Literature evidence available