G2W (p.Gly2Trp) variant of LCK (Tyrosine-protein kinase Lck)
G2W (p.Gly2Trp) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G2W (p.Gly2Trp) variant details
- p.Gly2Trp
- gnomAD 1-32274201-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- CADD 7.39
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.243
- Literature evidence available