G2A (p.Gly2Ala) variant of LCK (Tyrosine-protein kinase Lck)
G2A (p.Gly2Ala) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G2A (p.Gly2Ala) variant details
- p.Gly2Ala
- rs1280171764
- gnomAD 1-32274202-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- CADD 2.54
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.243
- Literature evidence available