E21E (p.Glu21Glu) variant of LCK (Tyrosine-protein kinase Lck)
E21E (p.Glu21Glu) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
E21E (p.Glu21Glu) variant details
- p.Glu21Glu
- gnomAD 1-32274392-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.255
- CADD 9.75
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.415
- Literature evidence available