D31D (p.Asp31Asp) variant of LCK (Tyrosine-protein kinase Lck)
D31D (p.Asp31Asp) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D31D (p.Asp31Asp) variant details
- p.Asp31Asp
- rs772820417
- gnomAD 1-32274284-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.219
- CADD 9.65
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.234
- Literature evidence available