D18E (p.Asp18Glu) variant of LCK (Tyrosine-protein kinase Lck)
D18E (p.Asp18Glu) in LCK (Tyrosine-protein kinase Lck) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D18E (p.Asp18Glu) variant details
- p.Asp18Glu
- gnomAD 1-32274269-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- CADD 8.98
- Population evidence available
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.725
- Literature evidence available