C3C (p.Cys3Cys) variant of LCK (Tyrosine-protein kinase Lck)
C3C (p.Cys3Cys) in LCK (Tyrosine-protein kinase Lck) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
C3C (p.Cys3Cys) variant details
- p.Cys3Cys
- rs1240141053
- gnomAD 1-32274338-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.279
- CADD 13.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- LCK SH3 domain domainome 1.0: score -0.113
- Literature evidence available