Y131F (p.Tyr131Phe) variant of LCAT (P04180)
Y131F (p.Tyr131Phe) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Y131F (p.Tyr131Phe) variant details
- p.Tyr131Phe
- gnomAD rs1329882443
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.31
- CADD 19.10
- PolyPhen-2 0.01
- SIFT 0.64
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available