W26C (p.Trp26Cys) variant of LCAT (P04180)
W26C (p.Trp26Cys) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
W26C (p.Trp26Cys) variant details
- p.Trp26Cys
- Ensembl rs2151322118
- Missense
- Variant Prioritization Score for Impact Estimate 0.811
- REVEL 0.82
- CADD 27.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available