V163L (p.Val163Leu) variant of LCAT (P04180)
V163L (p.Val163Leu) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
V163L (p.Val163Leu) variant details
- p.Val163Leu
- ExAC rs748994180
- TOPMed rs748994180
- gnomAD rs748994180
- Missense
- Variant Prioritization Score for Impact Estimate 0.685
- REVEL 0.64
- CADD 22.10
- PolyPhen-2 0.75
- SIFT 0.06
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available