T83S (p.Thr83Ser) variant of LCAT (P04180)
T83S (p.Thr83Ser) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
T83S (p.Thr83Ser) variant details
- p.Thr83Ser
- ExAC rs763589763
- gnomAD rs763589763
- Missense
- Variant Prioritization Score for Impact Estimate 0.619
- REVEL 0.51
- CADD 23.70
- PolyPhen-2 0.83
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.1e-05)
- Structural context available