T78I (p.Thr78Ile) variant of LCAT (P04180)
T78I (p.Thr78Ile) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
T78I (p.Thr78Ile) variant details
- p.Thr78Ile
- ExAC rs780912694
- Missense
- Variant Prioritization Score for Impact Estimate 0.734
- REVEL 0.71
- CADD 25.60
- PolyPhen-2 0.52
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available