T46I (p.Thr46Ile) variant of LCAT (P04180)
T46I (p.Thr46Ile) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
T46I (p.Thr46Ile) variant details
- p.Thr46Ile
- gnomAD rs1433630587
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.53
- CADD 24.50
- PolyPhen-2 0.96
- SIFT 0.06
- Population evidence available
- Structural context available