T162A (p.Thr162Ala) variant of LCAT (P04180)
T162A (p.Thr162Ala) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
T162A (p.Thr162Ala) variant details
- p.Thr162Ala
- gnomAD rs2058298709
- Missense
- Variant Prioritization Score for Impact Estimate 0.612
- REVEL 0.61
- CADD 22.90
- PolyPhen-2 0.70
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available