P24L (p.Pro24Leu) variant of LCAT (P04180)
P24L (p.Pro24Leu) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
P24L (p.Pro24Leu) variant details
- p.Pro24Leu
- Ensembl rs1051642208
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.36
- CADD 22.30
- PolyPhen-2 0.25
- SIFT 0.37
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available