N108S (p.Asn108Ser) variant of LCAT (P04180)
N108S (p.Asn108Ser) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
N108S (p.Asn108Ser) variant details
- p.Asn108Ser
- ExAC rs761902457
- gnomAD rs761902457
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.66
- CADD 25.30
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00052)
- Structural context available