K77Q (p.Lys77Gln) variant of LCAT (P04180)
K77Q (p.Lys77Gln) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
K77Q (p.Lys77Gln) variant details
- p.Lys77Gln
- ExAC rs746342275
- gnomAD rs746342275
- Missense
- Variant Prioritization Score for Impact Estimate 0.667
- REVEL 0.68
- CADD 27.10
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available