F91L (p.Phe91Leu) variant of LCAT (P04180)
F91L (p.Phe91Leu) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
F91L (p.Phe91Leu) variant details
- p.Phe91Leu
- gnomAD rs2058301852
- Missense
- Variant Prioritization Score for Impact Estimate 0.535
- REVEL 0.50
- CADD 20.10
- PolyPhen-2 0.19
- SIFT 1.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available