C74W (p.Cys74Trp) variant of LCAT (P04180)
C74W (p.Cys74Trp) in LCAT (P04180) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
C74W (p.Cys74Trp) variant details
- p.Cys74Trp
- gnomAD rs1242606598
- Missense
- Variant Prioritization Score for Impact Estimate 0.747
- REVEL 0.84
- CADD 27.40
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available